Why Are Cardiologists So Passionate About Exercise?

Published on 29 April 2025 at 22:11

Exercise is often referred to as a universal "medication," accessible to everyone globally. However, it must be tailored to individual needs, as certain health conditions should be considered before incorporating regular physical activity into daily routines.

 

Interestingly, there’s a parallel between the progression of cardiovascular disease and the decline in physical activity over a lifetime. Cardiovascular diseases, such as atherosclerosis (e.g., coronary artery disease, stroke, peripheral vascular disease), often develop as physical activity decreases with age.

 

Sedentary lifestyles can contribute to cellular stress—such as increased NADPH oxidase activity—which leads to the production of reactive oxygen species in blood vessels. This link has reinforced the belief among cardiologists that an active lifestyle is one of the most effective strategies for lifelong cardiovascular disease (CVD) prevention.

The Impact of Exercise on the Body

The Impact of Exercise on the Body
Exercise positively influences several risk factors for cardiovascular disease:
- Hypertension: Physical activity enhances endothelial function, optimizes sodium balance, modulates the renin-angiotensin system (which regulates blood pressure), and balances the sympathetic nervous system.

  • Diabetes: Exercise reduces insulin resistance by increasing muscle sensitivity to insulin, improving blood sugar regulation.
  • Cholesterol: Regular activity raises HDL (good cholesterol) and lowers LDL (bad cholesterol), promoting healthier lipid profiles.

Does Age Affect Exercise Benefits?

Each life stage offers unique opportunities and challenges for physical activity:

Pregnancy

Exercise reduces risks like gestational diabetes, excessive weight gain, preeclampsia, and preterm labor. However, more research is needed to confirm whether it lowers the long-term risk of obesity or diabetes in offspring.

Birth to 5 years

Movement is essential for motor development in early childhood. However, being overweight during this period can quadruple the risk of adolescent obesity and increase the likelihood of developing hypertension in adolescence and adulthood.

Ages 6-17 years

Staying active during childhood and adolescence is critical for preventing obesity, dyslipidemia, and hypertension in early adulthood. Unfortunately, many adolescents—particularly girls, youth with disabilities, those with obesity, and Hispanic youth—fall short of meeting physical activity guidelines in the United States.

Ages 18-44

While specific exercise recommendations for this age group are still under study, regular physical activity has been shown to lower systolic and diastolic blood pressure by 3-4 mmHg. It also reduces triglycerides, raises HDL, and stabilizes blood sugar levels, guarding against metabolic syndrome and atherosclerosis.

Ages 45-64

Hormonal changes and physiological shifts become more evident during this stage of life. Studies like ARIC and CARDIA have shown no racial differences in the benefits of physical activity for reducing CVD risk. Both men and women gain similar protective benefits against premature cardiovascular events.

A common claim during this stage is, "I exercise while working," which reflects the "Physical Activity Paradox." Unlike leisure-time physical activity, occupational activity often lacks comparable health benefits due to:

  • Insufficient intensity and frequency
  • Static postures and heavy lifting, which can raise blood pressure
  • Lack of recovery periods
  • Uncontrolled environmental factors (e.g., hydration, climate)
  • Prolonged activity, which may increase inflammation

Intentional exercise is still essential for maintaining metabolic health and preventing cardiovascular disease.

Ages 65 and older

Chronic conditions like osteoarthritis, diabetes, hypertension, and cancer are more prevalent with age. Cardiovascular aging also increases the risk of arrhythmias, arterial rigidity, and high blood pressure. For instance:

  • Over 65% of people in this age group are hypertensive.
  • 5-10% develop atrial fibrillation.
  • 10% have moderate-to-severe valvular disease or heart failure.

Even simple activities like walking offer substantial benefits. A 2023 meta-analysis published in Circulation found that older adults (≥60 years) who walked 6,000-9,000 steps daily reduced their CVD risk by 40-50% compared to those who walked fewer than 2,000 steps. Similarly, the Cardiovascular Health Study reported that older adults walking at least 49 blocks weekly reduced their risk of coronary heart disease, stroke, and CVD by 36-47% compared to those walking fewer than 5 blocks.

What About Physical Limitations?
While mobility challenges or joint pain may limit exercise options, walking remains a valuable and accessible activity unless joint problems are severe. For those with significant joint pain or overweight, water-based exercises provide a safe and effective alternative,

This opinion article has been documented from Perry AS, Dooley EE, Master H, Spartano NL, Brittain EL, Pettee Gabriel K.Physical Activity Over the Lifecourse and Cardiovascular Disease. Circ Res. 2023 Jun 9;132(12):1725-1740. doi: 10.1161/CIRCRESAHA.123.322121. Epub 2023 Jun 8.PMID: 37289900.

The images including in this article have been created in Canva using artificial intelligence.

By Dr. Romero Acero

 

 

 

Add comment

Comments

CARLOS ANDRES ROMERO ACERO
a month ago

Me parece que pa ser un inicio está bien. Tienes que irlo ampliarlo.

Jaime Romero
a month ago

Very usefull information related to the health benefits and excercise activities and age

Rocio Piamonte
a month ago

Very interesting article. It should motivate us to exercise more.

Rosario
a month ago

Es muy importante y todos debemos conocer acerca de los cuidados del corazón mediante el ejercicio y estilo de vida saludable, así reducimos los factores de riesgo de futuras comorbilidades.
Me gusto mucho el cuadro por grupo etario.
Muchas gracias por la información.