Exercise is often referred to as a universal "medication," accessible to everyone globally. However, it must be tailored to individual needs, as certain health conditions should be considered before incorporating regular physical activity into daily routines.
Interestingly, there’s a parallel between the progression of cardiovascular disease and the decline in physical activity over a lifetime. Cardiovascular diseases, such as atherosclerosis (e.g., coronary artery disease, stroke, peripheral vascular disease), often develop as physical activity decreases with age.
Sedentary lifestyles can contribute to cellular stress—such as increased NADPH oxidase activity—which leads to the production of reactive oxygen species in blood vessels. This link has reinforced the belief among cardiologists that an active lifestyle is one of the most effective strategies for lifelong cardiovascular disease (CVD) prevention.

The Impact of Exercise on the Body
The Impact of Exercise on the Body
Exercise positively influences several risk factors for cardiovascular disease:
- Hypertension: Physical activity enhances endothelial function, optimizes sodium balance, modulates the renin-angiotensin system (which regulates blood pressure), and balances the sympathetic nervous system.
- Diabetes: Exercise reduces insulin resistance by increasing muscle sensitivity to insulin, improving blood sugar regulation.
- Cholesterol: Regular activity raises HDL (good cholesterol) and lowers LDL (bad cholesterol), promoting healthier lipid profiles.
Does Age Affect Exercise Benefits?
Each life stage offers unique opportunities and challenges for physical activity:
This opinion article has been documented from Perry AS, Dooley EE, Master H, Spartano NL, Brittain EL, Pettee Gabriel K.Physical Activity Over the Lifecourse and Cardiovascular Disease. Circ Res. 2023 Jun 9;132(12):1725-1740. doi: 10.1161/CIRCRESAHA.123.322121. Epub 2023 Jun 8.PMID: 37289900.
The images including in this article have been created in Canva using artificial intelligence.
By Dr. Romero Acero
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Me parece que pa ser un inicio está bien. Tienes que irlo ampliarlo.
Very usefull information related to the health benefits and excercise activities and age
Very interesting article. It should motivate us to exercise more.
Es muy importante y todos debemos conocer acerca de los cuidados del corazón mediante el ejercicio y estilo de vida saludable, así reducimos los factores de riesgo de futuras comorbilidades.
Me gusto mucho el cuadro por grupo etario.
Muchas gracias por la información.